Parasites cause the vast majority of human interactions with flatworms. Flukes and tapeworms are the two groups of parasitic flatworms. And many can infect people sometimes causing disease.
Medical
Planaria are used as models for research. They are especially suited to test the toxicity of various chemicals. And they are also used as a model in neurological research.
Planaria are expert at regenerating. Here is a video about the processes that govern regeneration in planaria to understand if those processes can be replicated to help regenerate parts of the human body.